Asymmetric hydroamination
My group works on the asymmetric hydroamination reaction using chiral amino-alcohol ligands. The ligands are prepared in a few steps from naturally occurring amino acids. We have observed enantiomeric excesses of about 16% for the ring closing of 2-methyl-2,3-heptylamine (1,1-dimethyl-3-propylamino-allene...hmm, I wish we had a structure tool on the site...)
Adam Johnson / Harvey Mudd College
Fri, 03/14/2008 - 01:36
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