Cisplatin and Anticancer Therapy: The Role of Chemical Equilibrium

Submitted by Jack Eichler / University of California, Riverside on Thu, 02/20/2020 - 16:18
Description

This is a flipped classroom module that covers the concept of dynamic equilibrium, and how dynamic equlibrium plays a role in the anticancer mechanism of the therapeutic cisplatin.This activity is designed to be done at the end of the typical second quarter/second semester general chemistry equilibrium unit. Students will be expected to have learned the following concepts prior to completing this activity:

Formal oxidation states in Ru-catalyzed water oxidation
Description

This LO is an in-class assignment to prepare students for literature readings involving catalytic cycles in which multiple protons and electrons are transferred. Students practice assigning oxidation states to complexes with aquo, oxo, superoxo, and hydroperoxo ligands then use this information to analyze a proposed water oxidation mechanism from the literature.

Margaret Scheuermann / Western Washington University Fri, 01/17/2020 - 16:36

Time-Integrated Rate Laws and the Stability of Gold(III) Anticancer Compounds

Submitted by Jack Eichler / University of California, Riverside on Thu, 01/16/2020 - 14:55
Description

This is a flipped classroom module that covers the concepts of time-integrated rate laws. This activity is designed to be done at the end of the typical second quarter/second semester general chemistry kinetics unit. Students will be expected to have learned the following concepts prior to completing this activity:

Marvin suite from ChemAxon

Submitted by Anthony L. Fernandez / Merrimack College on Thu, 01/09/2020 - 12:10
Description

It is important for students to be able to effectively communicate the results of their scientific work. This does not only inlcude written and oral communication, but the creation of appropriate representations of the complexes they have investigated. It is crucial that students learn how to draw molecules using electronic structure drawing programs, but site licenses for structure drawing programs can be prohibitive for some institutions.

How to Read a Journal Article: Analyzing Author Roles and Article Components

Submitted by Catherine / East Tennessee State University on Wed, 01/08/2020 - 21:09
Description

This literature discussion uses a recently published article on solvatochromic Mo complexes to introduce students to the different components of a research article. The activity is divied into to two parts. Before class students read the paper and focus on defining terms, investigating the "meta" data of the paper, and the different sections iof the paper. In class the students work in groups to investigate the scientific content of the paper

Visualization of Solid State Structures using CrystalMaker and Physical Models

Submitted by Hilary Eppley / DePauw University on Wed, 01/08/2020 - 14:17
Description

This first-year laboratory is designed to give students an introduction to basic solid-state structures using both CrystalMaker files and physical models. I think this would work in a foundations level inorganic course as well. It could be used alternatively as an in-class activity or take-home problem set depending on the instructor. It was adapted by me and later, David Harvey, from an original activity that was posted as an educational resource on the CrystalMaker website in the mid 2000s.  

Reaction Mechanisms: Energy Profiles and Catalysts

Submitted by Wes Farrell / United States Naval Academy on Thu, 01/02/2020 - 13:44
Description

This in class activity consists of two demonstrations to be performed by the instructor, followed by a worksheet that students may work on independently or in groups.  The demonstrations allow the students to determine when a reaction has occured, when it has not occured, and generate qualitative reaction energy profiles to match these observations.  This activity is designed to take place during a description of kinetics in general chemistry. Detailed descriptions of the procedure and activity may be found in the "Overview for Instructor."

Mechanisms of Mn-catalyzed water oxidation reactions

Submitted by Margaret Scheuermann / Western Washington University on Fri, 10/18/2019 - 19:53
Description

This LO is an in-class assignment to prepare students for literature readings involving catalytic cycles in which multiple protons and electrons are transferred. Two catalytic mechanisms, a proposed OEC mechanism and the proposed mechanism of a biomimetic OEC complexes are included. The intermediates are drawn including all charges and oxidation states, details which are sometimes omitted in the primary literature but can be helpful to students who are not accustomed to looking at multistep catalytic cycles.

2019 Nobel Prize - Li-ion battery LOs

Submitted by Barbara Reisner / James Madison University on Wed, 10/09/2019 - 20:28

Congratulations to the 2019 recipients of the Nobel Prize - John B. Goodenough, M. Stan Whittingham and Akira Yoshino. It's a well deserved honor!

There are several LOs on VIPEr that talk about lithium ion batteries and related systems. The 2019 Nobel is a great opportunity to include something about these batteries in your class.

I hope to see more LOs in the coming weeks so we can bring this chemistry into our classrooms!