The Chemistry of Cooley's Anemia: A Case Study

Submitted by Chris Bailey / Wells College on Wed, 08/06/2014 - 11:36
Description

In this case study, information is presented to students in the form of a dialog between a physician and two parents who have just learned that their child has thalassemia (Cooley’s Anemia). The treatment for this disorder requires a lifetime commitment to whole blood transfusion and chelation therapy (both administered on a daily to weekly basis); the biggest obstacle to long term survival is patient non-compliance.

C&E News as a Starting Point for Bioinorganic Literature Discussions

Submitted by Chris Bailey / Wells College on Mon, 07/28/2014 - 15:37
Description

This learning object consists of a bibliography of materials concerning bioinorganic chemistry which have appeared in C&E News over approximately the past 15 years (1999-2014). Many come from the Science and Technology Concentrates, some from News of the Week, others are full articles, and a few are letters to the editor. They cover a wide variety of bioinorganic topics. Also included are citations for the articles from the primary literature paper referred to in the respective C&E News articles.

A cuprous azide complex: The effect of structure on the stability of the azide ion

Submitted by Jim Jeitler / Marietta College on Thu, 07/17/2014 - 17:50
Description

This is a problem set based on the article "Energetic Cuprous Azide Complex: Synthesis, Crystal Structure and Effection on the Thermal Decomposition of HMX" in the Journal of Chemical Crystallography.  It has been used in a Chemistry Capstone course for both Chemistry and Biochemistry majors during the first semester senior year.  Biochemistry majors are not required to take Inorganic Chemistry and Chemistry majors may be currently taking Inorganic chemistry.

Cobalt Schiff Base Zinc Finger Inhibitors

Submitted by Peter Craig / McDaniel College on Thu, 07/17/2014 - 13:08
Description

This is a literature discussion based on the paper “Spectroscopic Elucidation of the Inhibitory Mechanism of Cys2

The Synthesis and Characterization of a trans-Dioxorhenium(V) Complex

Submitted by Sibrina Collins / Marburger STEM Center (MSC) at Lawrence Technological University on Mon, 07/14/2014 - 12:31
Description

This experiment involves the preparation of a key starting reactant in high purity and yield for an ongoing research project, specifically for the development of potential photodynamic therapy (PDT) agents. The students synthesize [ReO2(py)4]Cl.2H2O using standard inorganic synthesis techniques. The students visualize the vibrations and electronic properties (e.g. molecular orbitals) of the compound using output files generated from density functional theory (DFT).

Coordination Diversity and Biological Activity of a Monodentate Au(III) Compound

Submitted by Sibrina Collins / Marburger STEM Center (MSC) at Lawrence Technological University on Thu, 07/10/2014 - 13:21
Description

 

This learning object focuses on a recent publication (Acta Crystallographia 2014, C70, 260 -266) by the Collins research group in the Department of Chemistry at The College of Wooster.  Specifically, the paper evaluates the coordination diversity of a N-donor ligand, 2-phenyl-1,10-phenanthroline(pnp) with three new pnp-metal complexes containing Au(III), Cu(II), and Pd(II) metal centers.

Cmap: Concept Mapping Tool

Submitted by Amanda Reig / Ursinus College on Thu, 06/27/2013 - 16:17
Description

Cmap Tools is a powerful free program that can be used to create concept maps.  The program works on any platform.

Thanks to Kurt Birdwhistell for posting the link to this tool to the forum a while back.

Building hybrid nanoparticles

Submitted by Angela Jovanovic-Bischof / Penn State on Thu, 06/27/2013 - 15:02
Description

This in-class activity was created at the NSF-TUES sponsored workshop at Penn State, June 2013.  It is based on the article from Ray Schaak’s group (Buck, Matthew R.; Bondi, James F.; Schaak, Raymond E. “A total-synthesis framework for the construction of high-order colloidal hybrid nanoparticles” Nature Chemistry 20124, 37-44, DOI: 10.1038/NCHEM.1195), which Ray presented at the workshop.

Defining Crystalline/Amorphous Phases of Nanoparticles through X-ray Absorption Spectroscopy and X-ray Diffraction: The Case of Nickel Phosphide

Submitted by Carrie Read Spray / Eastern Nazarene College on Thu, 06/27/2013 - 13:30
Description

This literature discussion activity is designed to highlight the use of different instrumentation and what details can be gained from each instrument.  It should also help the students review their knowledge of crystal structure, types of crystals, and amorphous solids.  The paper is from Chemistry of Materials, 2013, 25, 2394-2403 (DOI: 10.1021/cm303490y).  The paper should be given one week prior to class discussion, ideally after covering some of the instrumentation in class including X-ray dif

A Schaaking development of colloidal hybrid nanoparticles

Submitted by Anne Bentley / Lewis & Clark College on Thu, 06/27/2013 - 10:52
Description

This literature discussion was created at the NSF-TUES sponsored workshop at Penn State, June 2013.  It is based on the article from Ray Schaak’s group (Buck, Matthew R.; Bondi, James F.; Schaak, Raymond E. “A total-synthesis framework for the construction of high-order colloidal hybrid nanoparticles” Nature Chemistry, 2012 4, 37-44, DOI: 10.1038/NCHEM.1195), which Ray presented at the workshop.