My group works on the asymmetric hydroamination reaction using chiral amino-alcohol ligands. The ligands are prepared in a few steps from naturally occurring amino acids. We have observed enantiomeric excesses of about 16% for the ring closing of 2-methyl-2,3-heptylamine (1,1-dimethyl-3-propylamino-allene...hmm, I wish we had a structure tool on the site...)
I am not sure what you are asking above(structure tool?, xray diffractometer?), Adam.
Do you do your hydroaminations (intramolecular hydroamination?) in organic solvent or in an aqueous system?
In reply to asymmetric hydroamination by Kurt Birdwhistell / Loyola University New Orleans
I meant a chemical structure drawing tool for this website, so I could draw the reaction I am talking about.
We do our reactions in deuterated benzene, NMR tube scale.