In this experiment, students will synthesize and characterize one of three Ag(I) cyanoximate complexes as potential antimicrobial agents for use in dental implants. This experiment combines simple ligand synthesis, metalation and characterization, and a biomedical application. The complexes are both air and light stable.
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How much time to you devote to Bioinorganic Chemistry in your class?
This in-class activity requires that the students read an article in The Atlantic about an interesting (and modern) case of the plague. The article provides a great platform to showcase the Inorganic side of broad societal themes like evolutionary biology, environmental and hereditary influences on disease, and the collaboration between biology, medicine, and history. The article itself contains little chemistry, but can be used to guide students into learning about iron in bioinorganic chemistry.
Accompanying article found here: