9 Jul 2014

5 (or 6) Slides about Biophysical Techniques

Five Slides About

Submitted by Sheila Smith, University of Michigan- Dearborn
Categories
Description: 

This Five Slides About was prepared specifically for the 2014 IONiC/VIPEr workshop Bioinorganic Applications of Coordination Chemistry held at Northwestern University July 13-18, 2014.  

It covers, in one slide per technique, the techniques of electrochemistry (Cyclic Voltammetry), Electron Paramagnetic Resonance (EPR), Circular Dichroism (CD), X-ray Absorption Spectroscopy (XAS),  NMR (specifically 2D-NMR for structural information), Chemical Exchange Saturation Transfer (CEST).  This may seem an odd list, but it was chosen to prepare participants for the papers covered in the workshop.

It is intended to be paired with a collection of application assessment Questions, posted here on VIPEr, based on actual data from the literature.  I encourage VIPEr users to add your own!

 

These slides contain animations, so they are not very useful for printing out.  

Also, there is a LOT of information (references, teaching hints, etc ) in the NOTES section of the slides.  

Learning Goals: 
  •  A student should be able to explain the basics of each of the techniques included in this 5 Slides About:  CV, EPR, CEST, NMR, CD, and XAS and to apply these teachniques to the interpretation of real data.
Related activities: 
Implementation Notes: 

This LO is intended to be a quick introduction to the usefulness of these 6 techniques and their application to the characterization of bioinorganic samples.  

Ideally, one would cover each slide (each technique) and then offer students the opportunity to apply their new knowledge to a piece of real data from the literature.  I have posted several sets of Assessment Questions for that purpose.  

Time Required: 
a class period
Evaluation
Evaluation Methods: 

Assessment can be accomplished using the accompanying Assessment Questions linked to this LO and posted here on VIPEr.   I encourage others to add their own sets of Assessment question based on data in the literature.

Evaluation Results: 

This LO has not  been tested.

Creative Commons License: 
Creative Commons Licence

Comments

Very good presentation.

However, I would add a short stetement on CEST slide that:

"As of July 2014, no CEST or paraCEST contrast agents have been improved to be used in MRI of humans"

Sorry, I meant "approved".

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