19 Jul 2014

The "Zinc Spark" - Zinc as a signaling chemical in life

Web Resources and Apps

Submitted by Kyle Grice, DePaul University
Categories
Description: 

This web resource is a TEDx talk about zinc and zinc's role in the early stages of the maturation of the egg. This would be a great introduction video for a gen chem, inorganic, or bioinorganic chemistry course. It introduces the idea that Zinc is stored in specific locations on the egg and then released all at the same time.

It is not very long and should give the students lots of questions. Following this video, the students can do the related literature discussion and in-class activities on the O'Halloran Paper to obtain more bredth and in-depth work (see links in "related activities"). Directing students to O'Halloran's website is also an option in conjuction with haveing them see the video. 

It is a youtube video and should work on most electronic platforms.

Learning Goals: 

Students will be able to appreciate the role of Zinc as an important signalling chemical in biological systems

Students will identify when zinc fluxes occur early on in development

Students will recognize the important role of inorganic chemistry in multidisciplinary cutting edge research. 

Implementation Notes: 

Two group LOs were developed at the 2014 IONIC VIPER workshop relating to Tom O'Hallorans work, and this could be used to introduce O'Halloran and his work prior to giving the review chapter to read.

This video would also be excellent for gen chem or non-majors students who are interested in health to talk about inorganic chemisry in biology. You could also have a discussion on zinc sensors. Why do sensors need to be used? This gets into a discussion of metals in the cell, techniques, the specific properties of metals and complexes that can be measured, etc. 

Given its short time, students could also watch the video in class and then have the group discussion right there. 

Students can also be linked to O'halloran's website to learn more who he is about what he does. 

Time Required: 
20 min outside of class or in class
Evaluation
Evaluation Methods: 

Has not been evaluated yet, but I plan to have it included in the discussion of O'Halloran's review when I have it in my class. 

Creative Commons License: 
Creative Commons Licence

Comments

Kyle-  I would love to see a Literature discussion LO out of this!

Hi Sheila,

I will put that on my LO list. I would like to incorporate some other material in it as well (maybe one of the papers on Zinc sensors). I have another LO I want to get done first though.

-Kyle

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