This Five Slides About will introduce the basic photophysical and photochemical concepts associated with the metal-to-ligand charge-transfer (MLCT) transitions using luminescent rhenium and ruthenium complexes as examples. The potential therapeutic use of photoactivated metal complexes to kill cancer cells is also presented.
This LO is part of a special VIPEr collection honoring the 2022 ACS National Award recipients in the field of inorganic chemistry. Justin Wilson (Cornell University) was the recipient of the Harry Gray Award for Creative Work in Inorganic Chemistry by a Young Investigator for his interdisciplinary and broad-reaching research in the field of bioinorganic medicinal chemistry.
After viewing these slides, students should be able to:
- recall basic photophysical and photochemical concepts associated with MLCT states,
- explain photophysical and photophysical phenomena, including intersystem crossing, phosphorescence, singlet oxygen production, and photosubstitution using both molecular orbital diagrams and Jablonski diagrams, and
- recognize photoactive metal complexes that may have medicinal applications.
These slides can be used in a lecture setting or as a reference for teaching the concepts of metal-to-ligand charge-transfer (MLCT) transitions.
Since this is a slide deck intended for use in a presentation, the quality of these slides could be evaluated by the level and quality of the post-lecture discussion had by the students.
This LO has not been used in a classroom at this point in time so no evaluation has been done.